EC 3.1.3.11: Fructose-bisphosphatase
Reaction catalysed:
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate
Systematic name:
D-fructose-1,6-bisphosphate 1-phosphohydrolase
Alternative Name(s):
- D-fructose 1,6-diphosphatase
- D-fructose-1,6-bisphosphate phosphatase
- FBPase
- Fructose 1,6-bisphosphatase
- Fructose 1,6-bisphosphate 1-phosphatase
- Fructose 1,6-bisphosphate phosphatase
- Fructose 1,6-diphosphatase
- Fructose 1,6-diphosphate phosphatase
- Fructose bisphosphate phosphatase
- Fructose diphosphatase
- Fructose diphosphate phosphatase
- Hexose bisphosphatase
- Hexose diphosphatase
GO terms
Biochemical function:
Biological process:
- cellular response to phorbol 13-acetate 12-myristate
- cellular response to raffinose
- cellular hypotonic salinity response
- cellular hyperosmotic salinity response
- cellular response to xenobiotic stimulus
- cellular response to cAMP
- cellular response to magnesium ion
- negative regulation of Ras protein signal transduction
- negative regulation of glycolytic process
- cellular response to insulin stimulus
- response to nutrient levels
- fructose 1,6-bisphosphate metabolic process
- negative regulation of cell growth
- dephosphorylation
- regulation of gluconeogenesis
- gluconeogenesis
- fructose 6-phosphate metabolic process
- fructose metabolic process
- sucrose biosynthetic process
- carbohydrate metabolic process
- negative regulation of transcription by RNA polymerase II
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
Structure domains
CATH domains
3.40.190.80
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
D-Maltodextrin-Binding Protein; domain 2
Homology:
D-Maltodextrin-Binding Protein; domain 2
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4mjo</span> contains 8 copies of CATH domain <span class='highlight'>3.40.190.80 (D-Maltodextrin-Binding Protein; domain 2)</span> in <span class='highlight'>Fructose-1,6-bisphosphatase 1</span>. Showing 1 copy in chain <span class='highlight'>A</span>. The deposited structure of PDB entry 4mjo contains 8 copies of CATH domain 3.40.190.80 (D-Maltodextrin-Binding Protein; domain 2) in Fructose-1,6-bisphosphatase 1. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/4mjo_1_A_CATH_3.40.190.80_image-200x200.png)