EC 2.7.1.1: Hexokinase
Reaction catalysed:
ATP + D-hexose = ADP + D-hexose 6-phosphate
Systematic name:
ATP:D-hexose 6-phosphotransferase
Alternative Name(s):
- ATP-dependent hexokinase
- Glucose ATP phosphotransferase
- Hexokinase (phosphorylating)
- Hexokinase D
- Hexokinase type I
- Hexokinase type II
- Hexokinase type III
- Hexokinase type IV
- Hexokinase type IV (glucokinase)
- Hexokinase type IV glucokinase
GO terms
Biochemical function:
Biological process:
- calcium ion import
- canonical glycolysis
- glucose 6-phosphate metabolic process
- regulation of insulin secretion
- carbohydrate phosphorylation
- positive regulation of glycogen biosynthetic process
- negative regulation of gluconeogenesis
- cellular response to leptin stimulus
- regulation of potassium ion transport
- glucose homeostasis
- cellular response to insulin stimulus
- positive regulation of insulin secretion
- hexose metabolic process
- response to glucose
- NADP+ metabolic process
- regulation of glycolytic process
- glycolytic process
- glucose catabolic process
- glucose metabolic process
- carbohydrate metabolic process
- intracellular glucose homeostasis
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotationsStructure domains
CATH domains
3.30.420.40
Class:
Alpha Beta
Architecture:
2-Layer Sandwich
Topology:
Nucleotidyltransferase; domain 5
Homology:
Nucleotidyltransferase; domain 5
Occurring in:
