› 4mna

X-ray diffraction
4Å resolution

Crystal structure of the free FLS2 ectodomains

Released:
DOI: 10.2210/pdb4mna/pdb
Model geometry
Fit model/data
PDB entry 4mna coloured by chain, front view.
PDB entry 4mna coloured by chain, side view.
PDB entry 4mna coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex.
Sun Y, Li L, Macho AP, Han Z, Hu Z, Zipfel C, Zhou JM, Chai J
Science 342 624-8 (2013)
PMID: 24114786

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190347 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
LRR receptor-like serine/threonine-protein kinase FLS2 Chain: A
Molecule details ›
Chain: A
Length: 662 amino acids
Theoretical weight: 72.43 KDa
Source organism: Arabidopsis thaliana
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9FL28 (Residues: 25-800; Coverage: 57%)
Gene names: At5g46330, FLS2, MPL12.13, MPL12.8
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand NAG 5 x NAG
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P3221
Unit cell:
a: 189.542Å b: 189.542Å c: 117.751Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.251 0.25 0.279
Expression system: Spodoptera frugiperda

Quick links

Citations

96 review citations

Growth-defense tradeoffs in plants: a balancing act to optimize fitness.
Huot et al. (2014)
95 more

6 mentions without citation

A molecular roadmap to the plant immune system.
Bentham et al. (2020)
5 more

PDB-REDO

The sliders below show the change in model quality between original PDB entry and the PDB-REDO entry

Model Geometry
 
 
Data not available
DNA/RNA Geometry
 
 
Data not available
Fit model/data
 
 
Data not available
PDB-REDO