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Structure of ricin A chain bound with 2-amino-4-oxo-N-(2-(3-phenylureido)ethyl)-3,4-dihydropteridine-7-carboxamide

X-ray diffraction
1.59Å resolution
PDB entry 4mx1 coloured by chain, front view.
PDB entry 4mx1 coloured by chain, side view.
PDB entry 4mx1 coloured by chain, top view.
Source organism: Ricinus communis
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Ricin A chain
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Multimeric state: monomeric
Accessible surface area: 13441.44 Å2
Buried surface area: 484.95 Å2
Dissociation area: 87.3 Å2
Dissociation energy (ΔGdiss): 1.41 kcal/mol
Dissociation entropy (TΔSdiss): 1.23 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-136287

Macromolecules

Ricin A chain
Chain: A
Length: 268 amino acids
Theoretical weight: 30.07 KDa
Source organism: Ricinus communis
Expression system: Escherichia coli
UniProt:
  • Canonical: P02879 (Residues: 36-302; Coverage: 49%)
Pfam: Ribosome inactivating protein
InterPro:
CATH:
Ricin A chain in PDB entry 4mx1, assembly 1, front view.
Ricin A chain in PDB entry 4mx1, assembly 1, side view.
Ricin A chain in PDB entry 4mx1, assembly 1, top view.
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