Function and Biology

MazF from S. aureus crystal form III, C2221, 2.7 A

Source organism: Staphylococcus aureus subsp. aureus N315
Biochemical function: RNA endonuclease activity
Biological process: rRNA catabolic process
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF02452
Domain description: PemK-like, MazF-like toxin of type II toxin-antitoxin system
Occurring in:
  1. Endoribonuclease MazF
The deposited structure of PDB entry 4mzp contains 8 copies of Pfam domain PF02452 (PemK-like, MazF-like toxin of type II toxin-antitoxin system) in Endoribonuclease MazF. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR003477
Domain description: mRNA interferase PemK-like
Occurring in:
  1. Endoribonuclease MazF
IPR011067
Domain description: Plasmid maintenance toxin/Cell growth inhibitor
Occurring in:
  1. Endoribonuclease MazF

Structure domain

CATH CATH domain
2.30.30.110
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 type barrels.
Occurring in:
  1. Endoribonuclease MazF
The deposited structure of PDB entry 4mzp contains 8 copies of CATH domain 2.30.30.110 (SH3 type barrels.) in Endoribonuclease MazF. Showing 1 copy in chain B.