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PcrB from Geobacillus kaustophilus, with bound G1P

Source organism: Geobacillus kaustophilus HTA426
Biochemical function: metal ion binding
Biological process: glycerophospholipid biosynthetic process
Cellular component: not assigned

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EC 2.5.1.n9: Heptaprenylglyceryl phosphate synthase

Reaction catalysed:
All-trans-heptaprenyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(all-trans-heptaprenyl)glycerol 1-phosphate
Systematic name:
All-trans-heptaprenyl diphosphate:sn-glycerol 1-phosphate heptaprenyltransferase
Alternative Name(s):
  • Glycerol-1-phosphate heptaprenyltransferase
  • HepGP synthase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF01884
Domain description: PcrB family
Occurring in:
  1. Heptaprenylglyceryl phosphate synthase
  2. Heptaprenylglyceryl phosphate synthase
The deposited structure of PDB entry 4nae contains 1 copy of Pfam domain PF01884 (PcrB family) in Heptaprenylglyceryl phosphate synthase. Showing 1 copy in chain A.
The deposited structure of PDB entry 4nae contains 1 copy of Pfam domain PF01884 (PcrB family) in Heptaprenylglyceryl phosphate synthase. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR008205
Domain description: Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase
Occurring in:
  1. Heptaprenylglyceryl phosphate synthase
  2. Heptaprenylglyceryl phosphate synthase
IPR039074
Domain description: GGGP/HepGP synthase group I
Occurring in:
  1. Heptaprenylglyceryl phosphate synthase
  2. Heptaprenylglyceryl phosphate synthase
IPR038597
Domain description: GGGP/HepGP synthase superfamily
Occurring in:
  1. Heptaprenylglyceryl phosphate synthase
  2. Heptaprenylglyceryl phosphate synthase

Structure domain

CATH CATH domain
3.20.20.390
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: FMN-linked oxidoreductases
Occurring in:
  1. Heptaprenylglyceryl phosphate synthase
  2. Heptaprenylglyceryl phosphate synthase
The deposited structure of PDB entry 4nae contains 1 copy of CATH domain 3.20.20.390 (TIM Barrel) in Heptaprenylglyceryl phosphate synthase. Showing 1 copy in chain A.
The deposited structure of PDB entry 4nae contains 1 copy of CATH domain 3.20.20.390 (TIM Barrel) in Heptaprenylglyceryl phosphate synthase. Showing 1 copy in chain B.

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