4njh

X-ray diffraction
1.9Å resolution

Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet and 6-carboxy-5,6,7,8-tetrahydropterin

Released:

Function and Biology Details

Reaction catalysed:
6-carboxy-5,6,7,8-tetrahydropterin = 7-carboxy-7-carbaguanine + NH(3)
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-494141 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
7-carboxy-7-deazaguanine synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 230 amino acids
Theoretical weight: 25.34 KDa
Source organism: Burkholderia multivorans ATCC 17616
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H3KB22 (Residues: 1-210; Coverage: 100%)
Gene names: BMULJ_00116, Bmul_3115, queE
Structure domains: Aldolase class I

Ligands and Environments


Cofactor: Ligand SAM 2 x SAM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P43212
Unit cell:
a: 119.129Å b: 119.129Å c: 103.363Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.148 0.147 0.174
Expression system: Escherichia coli