Function and Biology

Crystal structure of middle east respiratory syndrome coronavirus S2 protein fusion core

Source organism: Middle East respiratory syndrome-related coronavirus
Biochemical function: not assigned
Biological process: endocytosis involved in viral entry into host cell
Cellular component: virion membrane

Sequence family

InterPro InterPro annotations
IPR043473
Domain description: Spike glycoprotein S2 superfamily, coronavirus
Occurring in:
  1. Spike protein S2'
IPR002552
Domain description: Spike glycoprotein S2, coronavirus
Occurring in:
  1. Spike protein S2'
IPR044873
Domain description: Spike glycoprotein S2, coronavirus, heptad repeat 1
Occurring in:
  1. Spike protein S2'

Structure domain

CATH CATH domain
1.20.5.300
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Occurring in:
  1. Spike protein S2'
The deposited structure of PDB entry 4njl contains 1 copy of CATH domain 1.20.5.300 (Single alpha-helices involved in coiled-coils or other helix-helix interfaces) in Spike protein S2'. Showing 1 copy in chain A.