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Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF09011
Domain description: HMG-box domain
Occurring in:
  1. Transcription factor A, mitochondrial
The deposited structure of PDB entry 4nnu contains 2 copies of Pfam domain PF09011 (HMG-box domain) in Transcription factor A, mitochondrial. Showing 1 copy in chain A.

PF00505
Domain description: HMG (high mobility group) box
Occurring in:
  1. Transcription factor A, mitochondrial
The deposited structure of PDB entry 4nnu contains 2 copies of Pfam domain PF00505 (HMG (high mobility group) box) in Transcription factor A, mitochondrial. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR009071
Domain description: High mobility group box domain
Occurring in:
  1. Transcription factor A, mitochondrial
IPR036910
Domain description: High mobility group box domain superfamily
Occurring in:
  1. Transcription factor A, mitochondrial

Structure domain

CATH CATH domain
1.10.30.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: DNA Binding (I), subunit A
Homology: High mobility group box domain
Occurring in:
  1. Transcription factor A, mitochondrial
The deposited structure of PDB entry 4nnu contains 4 copies of CATH domain 1.10.30.10 (DNA Binding (I), subunit A) in Transcription factor A, mitochondrial. Showing 2 copies in chain A.

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