Function and Biology Details
Reactions catalysed:
S-adenosyl-L-methionine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125470 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ORF1ab
Molecule details ›
Chain: A
Length: 326 amino acids
Theoretical weight: 36.25 KDa
Source organism: Human betacoronavirus 2c EMC/2012
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpB1GAP
UniProt:
Sequence domains: Coronavirus papain-like peptidase
Structure domains:
Length: 326 amino acids
Theoretical weight: 36.25 KDa
Source organism: Human betacoronavirus 2c EMC/2012
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpB1GAP
UniProt:
- Canonical:
K0BWD0 (Residues: 1482-1801; Coverage: 5%)
Sequence domains: Coronavirus papain-like peptidase
Structure domains:
Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
PETRA III, DESY BEAMLINE P11
Spacegroup:
C2
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpB1GAP
