Function and Biology

Structure of Exomer bound to Arf1.

Source organisms:
Biochemical function: protein binding
Biological process: protein transport
Cellular component: Golgi apparatus

EC 3.6.5.2: Small monomeric GTPase

Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Systematic name:
GTP phosphohydrolase (cell-regulating)

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00025
Domain description: ADP-ribosylation factor family
Occurring in:
  1. ADP-ribosylation factor 1
The deposited structure of PDB entry 4q66 contains 4 copies of Pfam domain PF00025 (ADP-ribosylation factor family) in ADP-ribosylation factor 1. Showing 1 copy in chain I [auth F].

PF09295
Domain description: ChAPs (Chs5p-Arf1p-binding proteins)
Occurring in:
  1. Protein BCH1
The deposited structure of PDB entry 4q66 contains 4 copies of Pfam domain PF09295 (ChAPs (Chs5p-Arf1p-binding proteins)) in Protein BCH1. Showing 1 copy in chain E [auth K].

InterPro InterPro annotations
IPR006689
Domain description: Small GTPase superfamily, ARF/SAR type
Occurring in:
  1. ADP-ribosylation factor 1
IPR001357
Domain description: BRCT domain
Occurring in:
  1. Chs5p
IPR003961
Domain description: Fibronectin type III
Occurring in:
  1. Chs5p
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. ADP-ribosylation factor 1
IPR015374
Domain description: Chs5p-Arf1p binding
Occurring in:
  1. Protein BCH1
IPR036420
Domain description: BRCT domain superfamily
Occurring in:
  1. Chs5p
IPR031673
Domain description: Chitin biosynthesis protein Chs5, N-terminal
Occurring in:
  1. Chs5p
IPR045872
Domain description: ADP-ribosylation factor 1-5
Occurring in:
  1. ADP-ribosylation factor 1
IPR024156
Domain description: Small GTPase superfamily, ARF type
Occurring in:
  1. ADP-ribosylation factor 1
IPR005225
Domain description: Small GTP-binding protein domain
Occurring in:
  1. ADP-ribosylation factor 1
IPR011990
Domain description: Tetratricopeptide-like helical domain superfamily
Occurring in:
  1. Protein BCH1
IPR031669
Domain description: Fibronectin type III domain, fungi
Occurring in:
  1. Chs5p
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Chs5p
IPR036116
Domain description: Fibronectin type III superfamily
Occurring in:
  1. Chs5p

Structure domains

CATH CATH domains
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. ADP-ribosylation factor 1
The deposited structure of PDB entry 4q66 contains 4 copies of CATH domain 3.40.50.300 (Rossmann fold) in ADP-ribosylation factor 1. Showing 1 copy in chain I [auth F].
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. Chs5p
The deposited structure of PDB entry 4q66 contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Chs5p. Showing 1 copy in chain D.
6.20.120.50
Class: Special
Architecture: Other non-globular
Topology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Occurring in:
  1. Chs5p
The deposited structure of PDB entry 4q66 contains 2 copies of CATH domain 6.20.120.50 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in Chs5p. Showing 1 copy in chain D.