› 4qsl

X-ray diffraction
3.28Å resolution

Crystal Structure of Listeria Monocytogenes Pyruvate Carboxylase

Released:
DOI: 10.2210/pdb4qsl/pdb
PDB entry 4qsl coloured by chain, front view.
PDB entry 4qsl coloured by chain, side view.
PDB entry 4qsl coloured by chain, top view.
Source organism: Listeria monocytogenes
Primary publication:
The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function.
Sureka K, Choi PH, Precit M, Delince M, Pensinger DA, Huynh TN, Jurado AR, Goo YA, Sadilek M, Iavarone AT, Sauer JD, Tong L, Woodward JJ
Cell 158 1389-1401 (2014)
PMID: 25215494

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165127 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pyruvate carboxylase Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 1146 amino acids
Theoretical weight: 128.26 KDa
Source organism: Listeria monocytogenes
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P1
Unit cell:
a: 91.36Å b: 132.615Å c: 257.544Å
α: 86.65° β: 79.84° γ: 70.07°
R-values:
R R work R free
0.24 0.238 0.284
Expression system: Escherichia coli

Quick links

Citations

33 review citations

Cyclic di-GMP: second messenger extraordinaire.
Jenal et al. (2017)
32 more

1 mention without citation

The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function.
Sureka et al. (2014)