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4re9 Overview
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4re9</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Insulin-degrading enzyme</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID</span>;</li> <li class='image_legend_li'>10 copies of <span class='highlight'>DI(HYDROXYETHYL)ETHER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PENTAETHYLENE GLYCOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4re9_deposited_chain_front_image-800x800.png "PDB entry 4re9 coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4re9</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Insulin-degrading enzyme</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID</span>;</li> <li class='image_legend_li'>10 copies of <span class='highlight'>DI(HYDROXYETHYL)ETHER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PENTAETHYLENE GLYCOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4re9_deposited_chain_side_image-800x800.png "PDB entry 4re9 coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4re9</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Insulin-degrading enzyme</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID</span>;</li> <li class='image_legend_li'>10 copies of <span class='highlight'>DI(HYDROXYETHYL)ETHER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PENTAETHYLENE GLYCOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4re9_deposited_chain_top_image-800x800.png "PDB entry 4re9 coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4re9</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Insulin-degrading enzyme</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID</span>;</li> <li class='image_legend_li'>10 copies of <span class='highlight'>DI(HYDROXYETHYL)ETHER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PENTAETHYLENE GLYCOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4re9_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 4re9 coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4re9</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Insulin-degrading enzyme</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID</span>;</li> <li class='image_legend_li'>10 copies of <span class='highlight'>DI(HYDROXYETHYL)ETHER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PENTAETHYLENE GLYCOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4re9_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 4re9 coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4re9</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Insulin-degrading enzyme</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID</span>;</li> <li class='image_legend_li'>10 copies of <span class='highlight'>DI(HYDROXYETHYL)ETHER</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>PENTAETHYLENE GLYCOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4re9_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 4re9 coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Monomeric assembly 2 of PDB entry <span class='highlight'>4re9</span> contains 1 copy of <span class='highlight'>4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide</span>. Front view.</div>](https://www.ebi.ac.uk/pdbe/static/entry/4re9_entity_3_front_image-800x800.png "4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide in PDB entry 4re9, assembly 2, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>4re9</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-degrading enzyme</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID</span>;</li> <li class='image_legend_li'>6 copies of <span class='highlight'>DI(HYDROXYETHYL)ETHER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PENTAETHYLENE GLYCOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4re9_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Monomeric assembly 1 of PDB entry 4re9 coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>4re9</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-degrading enzyme</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID</span>;</li> <li class='image_legend_li'>6 copies of <span class='highlight'>DI(HYDROXYETHYL)ETHER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PENTAETHYLENE GLYCOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4re9_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Monomeric assembly 1 of PDB entry 4re9 coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>4re9</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-degrading enzyme</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID</span>;</li> <li class='image_legend_li'>6 copies of <span class='highlight'>DI(HYDROXYETHYL)ETHER</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>PENTAETHYLENE GLYCOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4re9_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Monomeric assembly 1 of PDB entry 4re9 coloured by chemically distinct molecules, top view.")