› 4rg5

X-ray diffraction
1.7Å resolution

Crystal Structure of S. Pombe SMN YG-Dimer

Released:
DOI: 10.2210/pdb4rg5/pdb
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PDB entry 4rg5 coloured by chain, front view.
PDB entry 4rg5 coloured by chain, side view.
PDB entry 4rg5 coloured by chain, top view.
Source organisms:
Primary publication:
Oligomeric Properties of Survival Motor Neuron·Gemin2 Complexes.
Gupta K, Martin R, Sharp R, Sarachan KL, Ninan NS, Van Duyne GD
J Biol Chem 290 20185-99 (2015)
PMID: 26092730

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142556 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Maltose/maltodextrin-binding periplasmic protein; SMN complex subunit smn1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 401 amino acids
Theoretical weight: 44.41 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P0AEX9 (Residues: 27-395; Coverage: 100%)
  • Canonical: Q09808 (Residues: 119-150; Coverage: 21%)
Gene names: JW3994, SPAC2G11.08c, b4034, malE, smn1, yab8
Sequence domains: Bacterial extracellular solute-binding protein

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
Carbohydrate polymer
2 bound ligands:
Ligand SO4 7 x SO4
Ligand MLI 2 x MLI
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 96.429Å b: 105.015Å c: 107.686Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.165 0.192
Expression system: Escherichia coli

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Citations

3 review citations

SMN - A chaperone for nuclear RNP social occasions?
Raimer et al. (2017)
2 more

4 mentions without citation

A novel human-specific splice isoform alters the critical C-terminus of Survival Motor Neuron protein.
Seo et al. (2016)
3 more

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