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Structure of TRF2/RAP1 secondary interaction binding site

Source organism: Homo sapiens
Biochemical function: protein homodimerization activity
Biological process: protection from non-homologous end joining at telomere
Cellular component: nucleus

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF08558
Domain description: Telomere repeat binding factor (TRF)
Occurring in:
  1. Telomeric repeat-binding factor 2
The deposited structure of PDB entry 4rqi contains 4 copies of Pfam domain PF08558 (Telomere repeat binding factor (TRF)) in Telomeric repeat-binding factor 2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR013867
Domain description: Telomere repeat-binding factor, dimerisation domain
Occurring in:
  1. Telomeric repeat-binding factor 2
IPR036507
Domain description: Telomere repeat-binding factor, dimerisation domain superfamily
Occurring in:
  1. Telomeric repeat-binding factor 2
IPR030657
Domain description: Telomeric repeat-binding factor 2
Occurring in:
  1. Telomeric repeat-binding factor 2

Structure domain

CATH CATH domain
1.25.40.210
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homology: Telomere repeat-binding factor, dimerisation domain
Occurring in:
  1. Telomeric repeat-binding factor 2
The deposited structure of PDB entry 4rqi contains 4 copies of CATH domain 1.25.40.210 (Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat) in Telomeric repeat-binding factor 2. Showing 1 copy in chain A.

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