Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Granulocyte-macrophage colony-stimulating factor
- Fibronectin type III superfamily
- Immunoglobulin-like fold
- Four-helical cytokine-like, core
- Fibronectin type III
- Short hematopoietin receptor, family 2, conserved site
- Type I cytokine receptor, cytokine-binding domain
- IL-3 receptor alpha chain, N-terminal
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137429 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
Molecule details ›
Chain: B
Length: 281 amino acids
Theoretical weight: 32.87 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt: Gene names: CSF2R, CSF2RA, CSF2RY
Sequence domains:
Length: 281 amino acids
Theoretical weight: 32.87 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt: Gene names: CSF2R, CSF2RA, CSF2RY
Sequence domains:
Granulocyte-macrophage colony-stimulating factor
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Granulocyte-macrophage colony-stimulating factor
Structure domains: Growth Hormone; Chain: A;
Length: 112 amino acids
Theoretical weight: 12.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P04141 (Residues: 31-142; Coverage: 88%)
Sequence domains: Granulocyte-macrophage colony-stimulating factor
Structure domains: Growth Hormone; Chain: A;
