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Escherichia coli alpha-2-macroglobulin activated by porcine elastase

Source organism: Escherichia coli K-12
Biochemical function: protein homodimerization activity
Biological process: negative regulation of peptidase activity
Cellular component: plasma membrane

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF17973
Domain description: Bacterial Alpha-2-macroglobulin MG10 domain
Occurring in:
  1. Alpha-2-macroglobulin
The deposited structure of PDB entry 4rtd contains 1 copy of Pfam domain PF17973 (Bacterial Alpha-2-macroglobulin MG10 domain) in Alpha-2-macroglobulin. Showing 1 copy in chain A.

PF21765
Domain description: A2MG, CUB domain
Occurring in:
  1. Alpha-2-macroglobulin

PF07678
Domain description: A-macroglobulin TED domain
Occurring in:
  1. Alpha-2-macroglobulin
The deposited structure of PDB entry 4rtd contains 1 copy of Pfam domain PF07678 (A-macroglobulin TED domain) in Alpha-2-macroglobulin. Showing 1 copy in chain A.

PF00207
Domain description: Alpha-2-macroglobulin family
Occurring in:
  1. Alpha-2-macroglobulin
The deposited structure of PDB entry 4rtd contains 1 copy of Pfam domain PF00207 (Alpha-2-macroglobulin family) in Alpha-2-macroglobulin. Showing 1 copy in chain A.

PF07703
Domain description: Alpha-2-macroglobulin bait region domain
Occurring in:
  1. Alpha-2-macroglobulin
The deposited structure of PDB entry 4rtd contains 1 copy of Pfam domain PF07703 (Alpha-2-macroglobulin bait region domain) in Alpha-2-macroglobulin. Showing 1 copy in chain A.

PF17962
Domain description: Bacterial macroglobulin domain 6
Occurring in:
  1. Alpha-2-macroglobulin
The deposited structure of PDB entry 4rtd contains 1 copy of Pfam domain PF17962 (Bacterial macroglobulin domain 6) in Alpha-2-macroglobulin. Showing 1 copy in chain A.

PF17972
Domain description: Bacterial Alpha-2-macroglobulin MG5 domain
Occurring in:
  1. Alpha-2-macroglobulin
The deposited structure of PDB entry 4rtd contains 1 copy of Pfam domain PF17972 (Bacterial Alpha-2-macroglobulin MG5 domain) in Alpha-2-macroglobulin. Showing 1 copy in chain A.

PF01835
Domain description: MG2 domain
Occurring in:
  1. Alpha-2-macroglobulin
The deposited structure of PDB entry 4rtd contains 1 copy of Pfam domain PF01835 (MG2 domain) in Alpha-2-macroglobulin. Showing 1 copy in chain A.

PF11974
Domain description: Bacterial alpha-2-macroglobulin MG3 domain
Occurring in:
  1. Alpha-2-macroglobulin
The deposited structure of PDB entry 4rtd contains 1 copy of Pfam domain PF11974 (Bacterial alpha-2-macroglobulin MG3 domain) in Alpha-2-macroglobulin. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

PF21142
Domain description: Bacterial alpha-2 macroglobulin MG2 domain
Occurring in:
  1. Alpha-2-macroglobulin

PF17970
Domain description: Bacterial Alpha-2-macroglobulin MG1 domain
Occurring in:
  1. Alpha-2-macroglobulin
The deposited structure of PDB entry 4rtd contains 1 copy of Pfam domain PF17970 (Bacterial Alpha-2-macroglobulin MG1 domain) in Alpha-2-macroglobulin. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

InterPro InterPro annotations
IPR001599
Domain description: Alpha-2-macroglobulin
Occurring in:
  1. Alpha-2-macroglobulin
IPR011625
Domain description: Alpha-2-macroglobulin, bait region domain
Occurring in:
  1. Alpha-2-macroglobulin
IPR041246
Domain description: Bacterial alpha-2-macroglobulin MG10 domain
Occurring in:
  1. Alpha-2-macroglobulin
IPR008930
Domain description: Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
Occurring in:
  1. Alpha-2-macroglobulin
IPR047565
Domain description: Alpha-macroglobulin-like, thiol-ester bond-forming region
Occurring in:
  1. Alpha-2-macroglobulin
IPR011626
Domain description: Alpha-macroglobulin-like, TED domain
Occurring in:
  1. Alpha-2-macroglobulin
IPR041462
Domain description: Bacterial Alpha-2-macroglobulin, MG6 domain
Occurring in:
  1. Alpha-2-macroglobulin
IPR041203
Domain description: Bacterial Alpha-2-macroglobulin, MG5 domain
Occurring in:
  1. Alpha-2-macroglobulin
IPR002890
Domain description: Macroglobulin domain
Occurring in:
  1. Alpha-2-macroglobulin
IPR021868
Domain description: Alpha-2-macroglobulin MG3 domain
Occurring in:
  1. Alpha-2-macroglobulin
IPR040639
Domain description: Alpha-2-macroglobulin, MG1 domain
Occurring in:
  1. Alpha-2-macroglobulin
IPR026284
Domain description: Alpha-2-macroglobulin, proteobacteria
Occurring in:
  1. Alpha-2-macroglobulin

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