Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Maltose/Cyclodextrin ABC transporter, substrate-binding protein
- GPCR, family 2, extracellular hormone receptor domain
- Pro-adrenomedullin
- GPCR family 2, extracellular hormone receptor domain superfamily
- Calcitonin/adrenomedullin
- GPCR, family 2, secretin-like, conserved site
- Receptor activity modifying protein
- RAMP domain superfamily
2 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130166 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Calcitonin gene-related peptide type 1 receptor; Maltose/maltodextrin-binding periplasmic protein; Receptor activity-modifying protein 2
Molecule details ›
Chain: A
Length: 591 amino acids
Theoretical weight: 66.31 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 591 amino acids
Theoretical weight: 66.31 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
- Canonical:
P0AEX9 (Residues: 26-392; Coverage: 99%) - Canonical: O60895 (Residues: 49-138; Coverage: 68%)
- Canonical: Q16602 (Residues: 31-144; Coverage: 26%)
Sequence domains:
Adrenomedullin
Molecule details ›
Chain: B
Length: 29 amino acids
Theoretical weight: 3.25 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 29 amino acids
Theoretical weight: 3.25 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P35318 (Residues: 119-146; Coverage: 17%)
Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
APS BEAMLINE 21-ID-G
Spacegroup:
P212121
Expression systems:
- Escherichia coli
- Not provided
