Function and Biology

T. Brucei Farnesyl Diphosphate Synthase Complexed with Risedronate

Source organism: Trypanosoma brucei
Biochemical function: metal ion binding
Biological process: farnesyl diphosphate biosynthetic process
Cellular component: cytoplasm

Sequence family

Pfam Protein family (Pfam)
PF00348
Domain description: Polyprenyl synthetase
Occurring in:
  1. Farnesyl pyrophosphate synthase
The deposited structure of PDB entry 4rxd contains 3 copies of Pfam domain PF00348 (Polyprenyl synthetase) in Farnesyl pyrophosphate synthase. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR033749
Domain description: Polyprenyl synthetase, conserved site
Occurring in:
  1. Farnesyl pyrophosphate synthase
IPR000092
Domain description: Polyprenyl synthetase
Occurring in:
  1. Farnesyl pyrophosphate synthase
IPR008949
Domain description: Isoprenoid synthase domain superfamily
Occurring in:
  1. Farnesyl pyrophosphate synthase
IPR039702
Domain description: Farnesyl pyrophosphate synthase-like
Occurring in:
  1. Farnesyl pyrophosphate synthase
IPR036393
Domain description: Acetylglutamate kinase-like superfamily
Occurring in:
  1. Farnesyl pyrophosphate synthase

Structure domain

CATH CATH domain
1.10.600.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Farnesyl Diphosphate Synthase
Homology: Farnesyl Diphosphate Synthase
Occurring in:
  1. Farnesyl pyrophosphate synthase
The deposited structure of PDB entry 4rxd contains 3 copies of CATH domain 1.10.600.10 (Farnesyl Diphosphate Synthase) in Farnesyl pyrophosphate synthase. Showing 1 copy in chain B.