Function and Biology

Crystal structure of FraC with DHPC bound (crystal form II)

Source organism: Actinia fragacea
Biochemical function: toxin activity
Biological process: transmembrane transport
Cellular component: pore complex

Sequence family

Pfam Protein family (Pfam)
PF06369
Domain description: Sea anemone cytotoxic protein
Occurring in:
  1. DELTA-actitoxin-Afr1a
The deposited structure of PDB entry 4tsp contains 2 copies of Pfam domain PF06369 (Sea anemone cytotoxic protein) in DELTA-actitoxin-Afr1a. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR015926
Domain description: Cytolysin/lectin
Occurring in:
  1. DELTA-actitoxin-Afr1a
IPR009104
Domain description: Sea anemone actinoporin-like
Occurring in:
  1. DELTA-actitoxin-Afr1a

Structure domain

CATH CATH domain
2.60.270.20
Class: Mainly Beta
Architecture: Sandwich
Topology: Mutm (Fpg) Protein; Chain: A, domain 2
Homology: Cytolysin/lectin
Occurring in:
  1. DELTA-actitoxin-Afr1a
The deposited structure of PDB entry 4tsp contains 2 copies of CATH domain 2.60.270.20 (Mutm (Fpg) Protein; Chain: A, domain 2) in DELTA-actitoxin-Afr1a. Showing 1 copy in chain A.