4u2n

X-ray diffraction
2.3Å resolution

Crystal structure of a complex of the Miz1- and Nac1 POZ domains.

Released:
Source organism: Homo sapiens
Primary publication:
Structures of heterodimeric POZ domains of Miz1/BCL6 and Miz1/NAC1.
Acta Crystallogr F Struct Biol Commun 70 1591-6 (2014)
PMID: 25484205

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-171529 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleus accumbens-associated protein 1; Zinc finger and BTB domain-containing protein 17 Chains: A, B
Molecule details ›
Chains: A, B
Length: 255 amino acids
Theoretical weight: 27.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13105 (Residues: 2-115; Coverage: 14%)
  • Canonical: Q96RE7 (Residues: 2-125; Coverage: 24%)
Gene names: BTBD14B, MIZ1, NAC1, NACC1, ZBTB17, ZNF151, ZNF60
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21212
Unit cell:
a: 109.09Å b: 115.19Å c: 58.29Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.238 0.286
Expression system: Escherichia coli BL21(DE3)