EC 1.10.5.1: Ribosyldihydronicotinamide dehydrogenase (quinone)
Reaction catalysed:
1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a quinol
Systematic name:
1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase
Alternative Name(s):
- N-ribosyldihydronicotinamide dehydrogenase (quinone)
- NAD(P)H:quinone oxidoreductase(2)
- NAD(P)H:quinone oxidoreductase-2
- NQO(2)
- NQO2
- NRH:quinone oxidoreductase 2
- QR(2)
- QR2
- Quinone reductase 2
GO terms
Biochemical function:
- resveratrol binding
- melatonin binding
- FAD binding
- metal ion binding
- protein homodimerization activity
- chloride ion binding
- oxidoreductase activity, acting on other nitrogenous compounds as donors
- oxidoreductase activity
- electron transfer activity
- zinc ion binding
- protein binding
- NAD(P)H dehydrogenase (quinone) activity
- dihydronicotinamide riboside quinone reductase activity
Protein family (Pfam)![The deposited structure of PDB entry 4u7g contains 2 copies of Pfam domain PF02525 (Flavodoxin-like fold) in Ribosyldihydronicotinamide dehydrogenase [quinone]. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/4u7g_1_A_Pfam_PF02525_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>4u7g</span> contains 2 copies of Pfam domain <span class='highlight'>PF02525 (Flavodoxin-like fold)</span> in <span class='highlight'>Ribosyldihydronicotinamide dehydrogenase [quinone]</span>. Showing 1 copy in chain <span class='highlight'>A</span>.")
InterPro annotations
CATH domain![The deposited structure of PDB entry 4u7g contains 2 copies of CATH domain 3.40.50.360 (Rossmann fold) in Ribosyldihydronicotinamide dehydrogenase [quinone]. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/4u7g_1_A_CATH_3.40.50.360_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>4u7g</span> contains 2 copies of CATH domain <span class='highlight'>3.40.50.360 (Rossmann fold)</span> in <span class='highlight'>Ribosyldihydronicotinamide dehydrogenase [quinone]</span>. Showing 1 copy in chain <span class='highlight'>A</span>.")