4ubf

X-ray diffraction
3Å resolution

HsMCAK motor domain complex

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero trimer (preferred)
homo dimer
PDBe Complex ID:
PDB-CPX-189239 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Kinesin-like protein KIF2C Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 387 amino acids
Theoretical weight: 43.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q99661 (Residues: 225-593; Coverage: 51%)
Gene names: KIF2C, KNSL6
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain
Kinesin-like protein KIF2C Chain: P
Molecule details ›
Chain: P
Length: 12 amino acids
Theoretical weight: 1.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q99661 (Residues: 709-720; Coverage: 2%)
Gene names: KIF2C, KNSL6

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P21
Unit cell:
a: 46.306Å b: 245.644Å c: 79.399Å
α: 90° β: 95.84° γ: 90°
R-values:
R R work R free
0.265 0.264 0.286
Expression system: Escherichia coli BL21