EC 1.2.99.7: Aldehyde dehydrogenase (FAD-independent)
Reaction catalysed:
An aldehyde + H(2)O + acceptor = a carboxylate + reduced acceptor
Systematic name:
Aldehyde:acceptor oxidoreductase (FAD-independent)
Alternative Name(s):
- AORDd
- Aldehyde oxidase
- Aldehyde oxidoreductase
- Mop
GO terms
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence families
Protein families (Pfam)
InterPro annotations
IPR046867
Domain description:
Aldehyde oxidase/xanthine dehydrogenase, second molybdopterin binding domain
Occurring in:
Occurring in:
IPR008274
Domain description:
Aldehyde oxidase/xanthine dehydrogenase, first molybdopterin binding domain
Occurring in:
Occurring in:
IPR037165
Domain description:
Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily
Occurring in:
Occurring in:
IPR036856
Domain description:
Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily
Occurring in:
Occurring in:
Structure domains
CATH domains
3.30.365.10
Class:
Alpha Beta
Architecture:
2-Layer Sandwich
Topology:
Aldehyde Oxidoreductase; domain 4
Homology:
Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4usa</span> contains 4 copies of CATH domain <span class='highlight'>3.30.365.10 (Aldehyde Oxidoreductase; domain 4)</span> in <span class='highlight'>Aldehyde oxidoreductase</span>. Showing 4 copies in chain <span class='highlight'>A</span>. The deposited structure of PDB entry 4usa contains 4 copies of CATH domain 3.30.365.10 (Aldehyde Oxidoreductase; domain 4) in Aldehyde oxidoreductase. Showing 4 copies in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/4usa_1_A_CATH_3.30.365.10_image-200x200.png)
3.90.1170.50
Class:
Alpha Beta
Architecture:
Alpha-Beta Complex
Topology:
Aldehyde Oxidoreductase; domain 3
Homology:
Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4usa</span> contains 1 copy of CATH domain <span class='highlight'>3.90.1170.50 (Aldehyde Oxidoreductase; domain 3)</span> in <span class='highlight'>Aldehyde oxidoreductase</span>. Showing 1 copy in chain <span class='highlight'>A</span>. The deposited structure of PDB entry 4usa contains 1 copy of CATH domain 3.90.1170.50 (Aldehyde Oxidoreductase; domain 3) in Aldehyde oxidoreductase. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/4usa_1_A_CATH_3.90.1170.50_image-200x200.png)
1.10.150.120
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
DNA polymerase; domain 1
Homology:
[2Fe-2S]-binding domain
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4usa</span> contains 1 copy of CATH domain <span class='highlight'>1.10.150.120 (DNA polymerase; domain 1)</span> in <span class='highlight'>Aldehyde oxidoreductase</span>. Showing 1 copy in chain <span class='highlight'>A</span>. The deposited structure of PDB entry 4usa contains 1 copy of CATH domain 1.10.150.120 (DNA polymerase; domain 1) in Aldehyde oxidoreductase. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/4usa_1_A_CATH_1.10.150.120_image-200x200.png)