Function and Biology

STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I IODIDE COMPLEX - 2.3A

Source organism: Homo sapiens
Biochemical function: hydrolase activity
Biological process: not assigned
Cellular component: not assigned

EC 3.1.1.98: [Wnt protein] O-palmitoleoyl-L-serine hydrolase

Reaction catalysed:
[Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine + H(2)O = [Wnt]-L-serine + (9Z)-hexadec-9-enoate
Systematic name:
[Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine acylhydrolase
Alternative Name(s):
  • Notum

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF03283
Domain description: Pectinacetylesterase
Occurring in:
  1. Palmitoleoyl-protein carboxylesterase NOTUM
The deposited structure of PDB entry 4uyu contains 2 copies of Pfam domain PF03283 (Pectinacetylesterase) in Palmitoleoyl-protein carboxylesterase NOTUM. Showing 1 copy in chain A.

InterPro InterPro annotation
IPR004963
Domain description: Pectinacetylesterase/NOTUM
Occurring in:
  1. Palmitoleoyl-protein carboxylesterase NOTUM