Reviews - 4v05 mentioned but not cited (4)
- Fibroblast Growth Factor Receptors (FGFRs): Structures and Small Molecule Inhibitors. Dai S, Zhou Z, Chen Z, Xu G, Chen Y. Cells 8 E614 (2019)
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- Signaling Pathway and Small-Molecule Drug Discovery of FGFR: A Comprehensive Review. Zheng J, Zhang W, Li L, He Y, Wei Y, Dang Y, Nie S, Guo Z. Front Chem 10 860985 (2022)
- Synthetic Heterocyclic Derivatives as Kinase Inhibitors Tested for the Treatment of Neuroblastoma. Musumeci F, Cianciusi A, D'Agostino I, Grossi G, Carbone A, Schenone S. Molecules 26 7069 (2021)
Articles - 4v05 mentioned but not cited (11)
- Ensemble-Based Replica Exchange Alchemical Free Energy Methods: The Effect of Protein Mutations on Inhibitor Binding. Bhati AP, Wan S, Coveney PV. J Chem Theory Comput 15 1265-1277 (2019)
- Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer. Nakamura IT, Kohsaka S, Ikegami M, Ikeuchi H, Ueno T, Li K, Beyett TS, Koyama T, Shimizu T, Yamamoto N, Takahashi F, Takahashi K, Eck MJ, Mano H. NPJ Precis Oncol 5 66 (2021)
- Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. Ashraf-Uz-Zaman M, Shahi S, Akwii R, Sajib MS, Farshbaf MJ, Kallem RR, Putnam W, Wang W, Zhang R, Alvina K, Trippier PC, Mikelis CM, German NA. Eur J Med Chem 209 112866 (2021)
- Design, synthesis and biological evaluation of novel 1H-1,2,4-triazole, benzothiazole and indazole-based derivatives as potent FGFR1 inhibitors viafragment-based virtual screening. Liu J, Wen Y, Gao L, Gao L, He F, Zhou J, Wang J, Dai R, Chen X, Kang D, Hu L. J Enzyme Inhib Med Chem 35 72-84 (2020)
- Design, synthesis and biological evaluation of 4-bromo-N-(3,5-dimethoxyphenyl)benzamide derivatives as novel FGFR1 inhibitors for treatment of non-small cell lung cancer. Xie Z, Cheng D, Luo L, Shen G, Pan S, Pan Y, Chen B, Wang X, Liu Z, Zhang Y, Ye F. J Enzyme Inhib Med Chem 33 905-919 (2018)
- Structural and dynamic determinants for highly selective RET kinase inhibition reveal cryptic druggability. Shehata MA, Contreras J, Martín-Hurtado A, Froux A, Mohamed HT, El-Sherif AA, Plaza-Menacho I. J Adv Res 45 87-100 (2023)
- A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis. Bi Y, Zheng R, Hu J, Shi R, Shi J, Wang Y, Wang P, Jiang W, Kim G, Liu Z, Li X, Lin L. Genes Dis 11 479-494 (2024)
- Computational approach in searching for dual action multitarget inhibitors for osteosarcoma. Gani MA, Nurhan AD, Hadinar Putri BRK, Suyatno A, Khan SA, Ardianto C, Rantam FA, Khotib J. J Adv Pharm Technol Res 14 18-23 (2023)
- Discovery of Novel Naphthoquinone-Chalcone Hybrids as Potent FGFR1 Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling. Leechaisit R, Mahalapbutr P, Boonsri P, Karnchanapandh K, Rungrotmongkol T, Prachayasittikul V, Prachayasittikul S, Ruchirawat S, Prachayasittikul V, Pingaew R. ACS Omega 8 32593-32605 (2023)
- Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and in vivo study. Wei P, Liu B, Wang R, Gao Y, Li L, Ma Y, Qian Z, Chen Y, Cheng M, Geng M, Shen J, Zhao D, Ai J, Xiong B. Acta Pharm Sin B 9 351-368 (2019)
- The Hypoglycemic Effect of JinQi Jiangtang Tablets Is Partially Dependent on the Palmatine-Induced Activation of the Fibroblast Growth Factor Receptor 1 Signaling Pathway. Li S, Li X, Wang H, Jia X, Mao H, Dong F, Zhao T, Gao Y, Zhang C, Bai R, Liu R, Yan L, Ji Y, Zhang N, Wang W. Front Pharmacol 13 895724 (2022)
Reviews citing this publication (9)
- Small molecules in targeted cancer therapy: advances, challenges, and future perspectives. Zhong L, Li Y, Xiong L, Wang W, Wu M, Yuan T, Yang W, Tian C, Miao Z, Wang T, Yang S. Signal Transduct Target Ther 6 201 (2021)
- Management of advanced non-small cell lung cancers with known mutations or rearrangements: latest evidence and treatment approaches. Shea M, Costa DB, Rangachari D. Ther Adv Respir Dis 10 113-129 (2016)
- FGF19-FGFR4 Signaling in Hepatocellular Carcinoma. Raja A, Park I, Haq F, Ahn SM. Cells 8 E536 (2019)
- FGFR-TKI resistance in cancer: current status and perspectives. Yue S, Li Y, Chen X, Wang J, Li M, Chen Y, Wu D. J Hematol Oncol 14 23 (2021)
- The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives. Santolla MF, Maggiolini M. Cancers (Basel) 12 E3029 (2020)
- An overview of the binding models of FGFR tyrosine kinases in complex with small molecule inhibitors. Cheng W, Wang M, Tian X, Zhang X. Eur J Med Chem 126 476-490 (2017)
- Recent Studies on Ponatinib in Cancers Other Than Chronic Myeloid Leukemia. Musumeci F, Greco C, Grossi G, Molinari A, Schenone S. Cancers (Basel) 10 E430 (2018)
- Evaluation of Substituted Pyrazole-Based Kinase Inhibitors in One Decade (2011-2020): Current Status and Future Prospects. El-Gamal MI, El-Gamal MI, Zaraei SO, Madkour MM, Anbar HS. Molecules 27 330 (2022)
- Making way for suppressing the FGF19/FGFR4 axis in cancer. Prieto-Dominguez N, Shull AY, Teng Y. Future Med Chem 10 2457-2470 (2018)
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- Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use. Patani H, Bunney TD, Thiyagarajan N, Norman RA, Ogg D, Breed J, Ashford P, Potterton A, Edwards M, Williams SV, Thomson GS, Pang CS, Knowles MA, Breeze AL, Orengo C, Phillips C, Katan M. Oncotarget 7 24252-24268 (2016)
- Illuminating the molecular mechanisms of tyrosine kinase inhibitor resistance for the FGFR1 gatekeeper mutation: the Achilles' heel of targeted therapy. Sohl CD, Ryan MR, Luo B, Frey KM, Anderson KS. ACS Chem Biol 10 1319-1329 (2015)
- Dual Targeting of PDGFRα and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors. Wong JP, Todd JR, Finetti MA, McCarthy F, Broncel M, Vyse S, Luczynski MT, Crosier S, Ryall KA, Holmes K, Payne LS, Daley F, Wai P, Jenks A, Tanos B, Tan AC, Natrajan RC, Williamson D, Huang PH. Cell Rep 17 1265-1275 (2016)
- Fibroblast growth factor receptor 3 isoforms: Novel therapeutic targets for hepatocellular carcinoma? Paur J, Nika L, Maier C, Moscu-Gregor A, Kostka J, Huber D, Mohr T, Heffeter P, Schrottmaier WC, Kappel S, Kandioler D, Holzmann K, Marian B, Berger W, Grusch M, Grasl-Kraupp B. Hepatology 62 1767-1778 (2015)
- FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis. Turunen SP, von Nandelstadh P, Öhman T, Gucciardo E, Seashore-Ludlow B, Martins B, Rantanen V, Li H, Höpfner K, Östling P, Varjosalo M, Lehti K. Cell Death Differ 26 2577-2593 (2019)
- Structural and dynamic insights into the energetics of activation loop rearrangement in FGFR1 kinase. Klein T, Vajpai N, Phillips JJ, Davies G, Holdgate GA, Phillips C, Tucker JA, Norman RA, Scott AD, Higazi DR, Lowe D, Thompson GS, Breeze AL. Nat Commun 6 7877 (2015)
- Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations. Choi JP, Wang R, Yang X, Wang X, Wang L, Ting KK, Foley M, Cogger V, Yang Z, Liu F, Han Z, Liu R, Baell J, Zheng X. Sci Adv 4 eaau0731 (2018)
- Crystal Structure of the FGFR4/LY2874455 Complex Reveals Insights into the Pan-FGFR Selectivity of LY2874455. Wu D, Guo M, Philips MA, Qu L, Jiang L, Li J, Chen X, Chen Z, Chen L, Chen Y. PLoS One 11 e0162491 (2016)
- 2-Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4. Knoepfel T, Furet P, Mah R, Buschmann N, Leblanc C, Ripoche S, Graus-Porta D, Wartmann M, Galuba I, Fairhurst RA. ACS Med Chem Lett 9 215-220 (2018)
- Fibroblast growth factor receptor 1 antagonism attenuates lipopolysaccharide-induced activation of hepatic stellate cells via suppressing inflammation. Lou D, Han J, Zhou L, Ma H, Xv J, Shou J, Xu Z, Jiang L, Qian Y. Exp Ther Med 16 2909-2916 (2018)
- Biophysical characterization of drug-resistant mutants of fibroblast growth factor receptor 1. Yoza K, Himeno R, Amano S, Kobashigawa Y, Amemiya S, Fukuda N, Kumeta H, Morioka H, Inagaki F. Genes Cells 21 1049-1058 (2016)
- Approaches to selective fibroblast growth factor receptor 4 inhibition through targeting the ATP-pocket middle-hinge region. Fairhurst RA, Knoepfel T, Leblanc C, Buschmann N, Gaul C, Blank J, Galuba I, Trappe J, Zou C, Voshol J, Genick C, Brunet-Lefeuvre P, Bitsch F, Graus-Porta D, Furet P. Medchemcomm 8 1604-1613 (2017)
- Theoretical studies on FGFR isoform selectivity of FGFR1/FGFR4 inhibitors by molecular dynamics simulations and free energy calculations. Fu W, Chen L, Wang Z, Kang Y, Wu C, Xia Q, Liu Z, Zhou J, Liang G, Cai Y. Phys Chem Chem Phys 19 3649-3659 (2017)
- AZD4547 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Inflammation: The Role of FGFR1 in Renal Tubular Epithelial Cells. Chen X, Zhang X, Xu J, Zhao Y, Bao J, Zheng Z, Han J. Drug Des Devel Ther 14 833-844 (2020)
- Mutation Detection of Fibroblast Growth Factor Receptor 3 for Infiltrative Hepatocellular Carcinoma by Whole-Exome Sequencing. Yan X, Shao C, Chen C, Chen J, Gu S, Huang L, Fu X, Zhao H, Qiu Y. Dig Dis Sci 62 407-417 (2017)
- Anti-Tumor Activity of AZD4547 Against NTRK1 Fusion Positive Cancer Cells Through Inhibition of NTRKs. Cho H, Kim N, Murakami T, Sim T. Front Oncol 11 757598 (2021)
- Computational Simulation Studies on the Binding Selectivity of 1-(1H-Benzimidazol-5-yl)-5-aminopyrazoles in Complexes with FGFR1 and FGFR4. Pan YL, Liu YL, Chen JZ. Molecules 23 E767 (2018)
- Discovery of Orally Bioavailable FGFR2/FGFR3 Dual Inhibitors via Structure-Guided Scaffold Repurposing Approach. Nguyen MH, Ye HF, Xu Y, Truong L, Horsey A, Zhao P, Styduhar ED, Frascella M, Leffet L, Federowicz K, Behshad E, Wang A, Zhang K, Witten MR, Qi C, Jalluri R, Lai CT, Atasoylu O, Harris JJ, Hess R, Lin L, Zhang G, Covington M, Diamond S, Yao W, Vechorkin O. ACS Med Chem Lett 14 312-318 (2023)
- Exploring the endogenous potential of Hemidesmus indicus against breast cancer using in silico studies and quantification of 2-hydroxy-4-methoxy benzaldehyde through RP-HPLC. Bansod AA, Ramasamy G, Nathan B, Kandhasamy R, Palaniappan M, Vichangal Pridiuldi S. 3 Biotech 11 235 (2021)
- Discovery of a new potent oxindole multi-kinase inhibitor among a series of designed 3-alkenyl-oxindoles with ancillary carbonic anhydrase inhibitory activity as antiproliferative agents. Ismail RSM, El Kerdawy AM, Soliman DH, Georgey HH, Abdel Gawad NM, Angeli A, Supuran CT. BMC Chem 17 81 (2023)
- Elucidating the potential effects of point mutations on FGFR3 inhibitor resistance via combined molecular dynamics simulation and community network analysis. Liu B, Ding J, Liu Y, Wu J, Wu X, Chen Q, Li W. J Comput Aided Mol Des 37 325-338 (2023)
- Inhibition of Cancer Cell Proliferation and Bacterial Growth by Silver(I) Complexes Bearing a CH3-Substituted Thiadiazole-Based Thioamide. Varna D, Geromichalou E, Karlioti G, Papi R, Dalezis P, Hatzidimitriou AG, Psomas G, Choli-Papadopoulou T, Trafalis DT, Angaridis PA. Molecules 28 336 (2023)
- Receptor-based pharmacophore modeling, molecular docking, synthesis and biological evaluation of novel VEGFR-2, FGFR-1, and BRAF multi-kinase inhibitors. Abdel-Mohsen HT, Ibrahim MA, Nageeb AM, El Kerdawy AM. BMC Chem 18 42 (2024)