› 4v16

X-ray diffraction
2.8Å resolution

KlHsv2 with loop 6CD replaced by a Gly-Ser linker

Released:
DOI: 10.2210/pdb4v16/pdb
PDB entry 4v16 coloured by chain, front view.
PDB entry 4v16 coloured by chain, side view.
PDB entry 4v16 coloured by chain, top view.
Source organism: Kluyveromyces lactis
Primary publication:
Characterization of PROPPIN-Phosphoinositide Binding and Role of Loop 6CD in PROPPIN-Membrane Binding.
Busse RA, Scacioc A, Krick R, Pérez-Lara Á, Thumm M, Kühnel K
Biophys J 108 2223-34 (2015)
PMID: 25954880

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-563657 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SVP1-like protein 2 Chain: A
Molecule details ›
Chain: A
Length: 330 amino acids
Theoretical weight: 37.56 KDa
Source organism: Kluyveromyces lactis
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q6CN23 (Residues: 1-256, 275-339; Coverage: 95%)
Gene names: HSV2, KLLA0E15972g
Sequence domains: PROPPIN

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P3121
Unit cell:
a: 101.7Å b: 101.7Å c: 78.03Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.198 0.239
Expression system: Escherichia coli BL21

Quick links

Citations

10 review citations

Emerging roles of ATG proteins and membrane lipids in autophagosome formation.
Nishimura et al. (2020)
9 more

1 mention without citation

Characterization of PROPPIN-Phosphoinositide Binding and Role of Loop 6CD in PROPPIN-Membrane Binding.
Busse et al. (2015)