4v6w

Electron Microscopy
6Å resolution

Structure of the D. melanogaster 80S ribosome

Released:
Source organism: Drosophila melanogaster
Related structures: EMD-5591

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 86-mer (preferred)
PDBe Complex ID:
PDB-CPX-110961 (preferred)
Entry contents:
80 distinct polypeptide molecules
6 distinct RNA molecules
Macromolecules (86 distinct):
Eukaryotic translation elongation factor 2 Chain: Az
Molecule details ›
Chain: Az
Length: 844 amino acids
Theoretical weight: 94.59 KDa
Source organism: Drosophila melanogaster
UniProt:
  • Canonical: P13060 (Residues: 1-844; Coverage: 100%)
Gene names: CG2238, EF2, Ef2b, eEF2
Sequence domains:
Small ribosomal subunit protein RACK1 Chain: Ag
Molecule details ›
Chain: Ag
Length: 318 amino acids
Theoretical weight: 35.66 KDa
Source organism: Drosophila melanogaster
UniProt:
  • Canonical: O18640 (Residues: 1-318; Coverage: 100%)
Gene names: CG7111, Rack1
Sequence domains: WD domain, G-beta repeat
Small ribosomal subunit protein uS10 Chain: AU
Small ribosomal subunit protein eS10A Chain: AK
Small ribosomal subunit protein uS11A Chain: AO
Small ribosomal subunit protein uS12 Chain: AX
Small ribosomal subunit protein eS12 Chain: AM
Small ribosomal subunit protein uS13 Chain: AS
Small ribosomal subunit protein uS14 Chain: Ad
Small ribosomal subunit protein uS15 Chain: AN
Small ribosomal subunit protein uS17 Chain: AL
Small ribosomal subunit protein eS17 Chain: AR
Small ribosomal subunit protein uS19 Chain: AP
Small ribosomal subunit protein eS19A Chain: AT
Small ribosomal subunit protein eS1 Chain: AB
Small ribosomal subunit protein uS2 Chain: AA
Small ribosomal subunit protein eS21 Chain: AV
40S ribosomal protein S24 Chain: AY
Small ribosomal subunit protein eS25 Chain: AZ
Small ribosomal subunit protein eS26 Chain: Aa
40S ribosomal protein S27 Chain: Ab
Small ribosomal subunit protein eS28 Chain: Ac
Small ribosomal subunit protein uS3 Chain: AD
Ribosomal protein S30, isoform C Chain: Ae
Small ribosomal subunit protein eS31 Chain: Af
Small ribosomal subunit protein uS4 Chain: AJ
Small ribosomal subunit protein eS4 Chain: AE
Small ribosomal subunit protein uS5 Chain: AC
Small ribosomal subunit protein eS6 Chain: AG
Small ribosomal subunit protein uS7A Chain: AF
Small ribosomal subunit protein eS7 Chain: AH
Small ribosomal subunit protein uS8A Chain: AW
Small ribosomal subunit protein eS8 Chain: AI
Small ribosomal subunit protein uS9 Chain: AQ
Hyaluronan/mRNA-binding protein domain-containing protein Chain: Ah
Large ribosomal subunit protein uL1 Chain: Cz
Large ribosomal subunit protein uL10 Chain: Cq
Large ribosomal subunit protein uL11 Chain: CK
Large ribosomal subunit protein uL13 Chain: CO
Large ribosomal subunit protein eL13 Chain: CL
Large ribosomal subunit protein uL14 Chain: CV
Large ribosomal subunit protein eL14 Chain: CM
Large ribosomal subunit protein uL15 Chain: Ca
Large ribosomal subunit protein eL15 Chain: CN
Large ribosomal subunit protein uL16 Chain: CI
Large ribosomal subunit protein uL18 Chain: CD
Large ribosomal subunit protein eL18 Chain: CQ
Large ribosomal subunit protein eL19 Chain: CR
Large ribosomal subunit protein uL2 Chain: CA
Large ribosomal subunit protein eL20 Chain: CS
60S ribosomal protein L21 Chain: CT
Large ribosomal subunit protein uL22 Chain: CP
Large ribosomal subunit protein eL22 Chain: CU
Large ribosomal subunit protein uL23 N-terminal domain-containing protein Chain: CX
KOW domain-containing protein Chain: CY
Large ribosomal subunit protein eL24 Chain: CW
60S ribosomal protein L27 Chain: CZ
Large ribosomal subunit protein eL28 Chain: Cr
Large ribosomal subunit protein uL29 Chain: Ch
Large ribosomal subunit protein eL29 Chain: Cb
Large ribosomal subunit protein uL3 Chain: CB
Large ribosomal subunit protein uL30 Chain: CF
Large ribosomal subunit protein eL30 Chain: Cc
Large ribosomal subunit protein eL31 Chain: Cd
Large ribosomal subunit protein eL32 Chain: Ce
Large ribosomal subunit protein eL33 Chain: Cf
Large ribosomal subunit protein eL34 Chain: Cg
Large ribosomal subunit protein eL36 Chain: Ci
Large ribosomal subunit protein eL37A Chain: Cj
Large ribosomal subunit protein eL38 Chain: Ck
Large ribosomal subunit protein eL39 Chain: Cl
Large ribosomal subunit protein uL4 Chain: CC
Large ribosomal subunit protein eL40 Chain: Cm
60S ribosomal protein L41 Chain: Cn
Large ribosomal subunit protein eL43 Chain: Cp
Ribosomal protein L36A, isoform A Chain: Co
Large ribosomal subunit protein uL5 Chain: CJ
Large ribosomal subunit protein uL6 Chain: CH
Large ribosomal subunit protein eL6 Chain: CE
Large ribosomal subunit protein eL8 Chain: CG
18S Ribosomal RNA Chain: B2
E-tRNA Chain: BC
28S ribosomal RNA Chain: A5
2S ribosomal RNA Chain: A9
5S ribosomal RNA Chain: A7
5.8S ribosomal RNA Chain: A8

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-5591