PDB 4w1o: PDE4D complexed with inhibitor | Protein Data Bank in Europe

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Entry title

PDE4D complexed with inhibitor

Source organism

Homo sapiens

Primary publication

Discovery and early clinical development of 2-{6-[2-(3,5-dichloro-4-pyridyl)acetyl]-2,3-dimethoxyphenoxy}-N-propylacetamide (LEO 29102), a soft-drug inhibitor of phosphodiesterase 4 for topical treatment of atopic dermatitis.

Felding J, Sørensen MD, Poulsen TD, Larsen J, Andersson C

J. Med. Chem. 57 5893-903 (2014) PMID 24984230

DOI 10.1021/jm500378a

Also associated with: 4wcu

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