› 4wsp

X-ray diffraction
1.65Å resolution

Racemic crystal structure of Rv1738 from Mycobacterium tuberculosis (Form-I)

Released:
DOI: 10.2210/pdb4wsp/pdb
PDB entry 4wsp coloured by chain, front view.
PDB entry 4wsp coloured by chain, side view.
PDB entry 4wsp coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Primary publication:
A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography.
Bunker RD, Mandal K, Bashiri G, Chaston JJ, Pentelute BL, Lott JS, Kent SB, Baker EN
Proc Natl Acad Sci U S A 112 4310-5 (2015)
PMID: 25831534

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-552199 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
protein DL-Rv1738 Chain: A
Molecule details ›
Chain: A
Length: 94 amino acids
Theoretical weight: 10.62 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Not provided
UniProt:
  • Canonical: P9WLS3 (Residues: 1-94; Coverage: 100%)
Gene names: MTCY04C12.23, Rv1738
Sequence domains: Rv2632c-like
Structure domains: Rv1738

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-BM-B
Spacegroup: C2/c
Unit cell:
a: 96.13Å b: 32.401Å c: 58.214Å
α: 90° β: 125.06° γ: 90°
R-values:
R R work R free
0.251 0.25 0.264
Expression system: Not provided

Quick links

Citations

7 review citations

Mycobacterial Dormancy Systems and Host Responses in Tuberculosis.
Peddireddy et al. (2017)
6 more

1 mention without citation

A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography.
Bunker et al. (2015)