Function and Biology

The crystal structure of hemagglutinin from A/Jiangxi-Donghu/346/2013 influenza virus

Source organism: Influenza A virus
Biochemical function: host cell surface receptor binding
Biological process: fusion of virus membrane with host plasma membrane
Cellular component: viral envelope

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00509
Domain description: Haemagglutinin
Occurring in:
  1. Hemagglutinin
  2. Hemagglutinin HA2 chain
The deposited structure of PDB entry 4wsx contains 12 copies of Pfam domain PF00509 (Haemagglutinin) in Hemagglutinin. Showing 1 copy in chain A.
The deposited structure of PDB entry 4wsx contains 12 copies of Pfam domain PF00509 (Haemagglutinin) in Hemagglutinin HA2 chain. Showing 1 copy in chain J.

InterPro InterPro annotations
IPR000149
Domain description: Haemagglutinin, influenzavirus A
Occurring in:
  1. Hemagglutinin
IPR001364
Domain description: Haemagglutinin, influenzavirus A/B
Occurring in:
  1. Hemagglutinin
  2. Hemagglutinin HA2 chain
IPR000386
Domain description: Haemagglutinin, influenzavirus B
Occurring in:
  1. Hemagglutinin HA2 chain
IPR013828
Domain description: Haemagglutinin, HA1 chain, alpha/beta domain superfamily
Occurring in:
  1. Hemagglutinin
IPR008980
Domain description: Viral capsid/haemagglutinin protein
Occurring in:
  1. Hemagglutinin

Structure domains

CATH CATH domains
2.10.77.10
Class: Mainly Beta
Architecture: Ribbon
Topology: Hemagglutinin; Chain A, domain 2
Homology: Hemagglutinin Chain A, Domain 2
Occurring in:
  1. Hemagglutinin
The deposited structure of PDB entry 4wsx contains 12 copies of CATH domain 2.10.77.10 (Hemagglutinin; Chain A, domain 2) in Hemagglutinin. Showing 1 copy in chain A.
3.90.20.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Hemagglutinin Ectodomain; Chain B
Homology: Hemagglutinin Ectodomain; Chain B
Occurring in:
  1. Hemagglutinin HA2 chain
The deposited structure of PDB entry 4wsx contains 12 copies of CATH domain 3.90.20.10 (Hemagglutinin Ectodomain; Chain B) in Hemagglutinin HA2 chain. Showing 1 copy in chain B.
3.90.209.20
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
Homology: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
Occurring in:
  1. Hemagglutinin
The deposited structure of PDB entry 4wsx contains 12 copies of CATH domain 3.90.209.20 (Hemagglutinin (Ha1 Chain); Chain: A; domain 1) in Hemagglutinin. Showing 1 copy in chain A.