› 4x08

X-ray diffraction
1.34Å resolution

Structure of H128N/ECP mutant in complex with sulphate anions at 1.34 Angstroms.

Released:
DOI: 10.2210/pdb4x08/pdb
PDB entry 4x08 coloured by chain, front view.
PDB entry 4x08 coloured by chain, side view.
PDB entry 4x08 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Blanco JA, Garcia JM, Salazar VA, Sanchez D, Moussauoi M, Boix E

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-536985 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eosinophil cationic protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 134 amino acids
Theoretical weight: 15.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12724 (Residues: 28-160; Coverage: 100%)
Gene names: ECP, RNASE3, RNS3
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

1 bound ligand:
Ligand SO4 16 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: C2
Unit cell:
a: 92.867Å b: 51.104Å c: 55.601Å
α: 90° β: 111.09° γ: 90°
R-values:
R R work R free
0.186 0.184 0.218
Expression system: Escherichia coli BL21(DE3)

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