Function and Biology

Crystal structure of human 4E10 Fab in complex with phosphatidylglycerol (06:0 PG)

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. 4E10 Fab heavy chain
  2. 4E10 Fab light chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. 4E10 Fab heavy chain
  2. 4E10 Fab light chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. 4E10 Fab heavy chain
  2. 4E10 Fab light chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. 4E10 Fab heavy chain
  2. 4E10 Fab light chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. 4E10 Fab heavy chain
  2. 4E10 Fab light chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. 4E10 Fab heavy chain
  2. 4E10 Fab light chain
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. 4E10 Fab heavy chain
  2. 4E10 Fab light chain

Structure domain

CATH CATH domain
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. 4E10 Fab heavy chain
  2. 4E10 Fab light chain
The deposited structure of PDB entry 4xcy contains 12 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in 4E10 Fab light chain. Showing 2 copies in chain C [auth B].
The deposited structure of PDB entry 4xcy contains 12 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in 4E10 Fab heavy chain. Showing 2 copies in chain D [auth A].