› 4yu6

X-ray diffraction
2.6Å resolution

Crystal structure of Bacillus anthracis immune inhibitor A2 peptidase zymogen

Released:
DOI: 10.2210/pdb4yu6/pdb
PDB entry 4yu6 coloured by chain, front view.
PDB entry 4yu6 coloured by chain, side view.
PDB entry 4yu6 coloured by chain, top view.
Source organism: Bacillus cereus biovar anthracis str. CI
Primary publication:
Structural Basis for Latency and Function of Immune Inhibitor A Metallopeptidase, a Modulator of the Bacillus anthracis Secretome.
Arolas JL, Goulas T, Pomerantsev AP, Leppla SH, Gomis-Rüth FX
Structure 24 25-36 (2016)
PMID: 26745529

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-241420 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immune inhibitor A, metalloprotease Chains: A, B
Molecule details ›
Chains: A, B
Length: 756 amino acids
Theoretical weight: 83.66 KDa
Source organism: Bacillus cereus biovar anthracis str. CI
Expression system: Bacillus subtilis

Ligands and Environments

5 bound ligands:
Ligand ZN 2 x ZN
Ligand CA 9 x CA
Ligand NA 2 x NA
Ligand CCN 3 x CCN
Ligand K 2 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 176.98Å b: 108.87Å c: 100.41Å
α: 90° β: 119.07° γ: 90°
R-values:
R R work R free
0.171 0.171 0.211
Expression system: Bacillus subtilis

Quick links

Citations

3 citation in other articles

In silico characterization and structural modeling of bacterial metalloprotease of family M4.
Hasan et al. (2021)
2 more

1 mention without citation

Structural Basis for Latency and Function of Immune Inhibitor A Metallopeptidase, a Modulator of the Bacillus anthracis Secretome.
Arolas et al. (2016)