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Serratia marcescens Chitinase B complexed with macrolide inhibitor 30

Source organism: Serratia marcescens
Biochemical function: carbohydrate binding
Biological process: carbohydrate metabolic process
Cellular component: extracellular region

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EC 3.2.1.14: Chitinase

Reaction catalysed:
Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins
Systematic name:
(1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase
Alternative Name(s):
  • 1,4-beta-poly-N-acetylglucosaminidase
  • Beta-1,4-poly-N-acetyl glucosamidinase
  • ChiC
  • Chitodextrinase
  • Poly(1,4-(N-acetyl-beta-D-glucosaminide)) glycanohydrolase
  • Poly-beta-glucosaminidase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF00704
Domain description: Glycosyl hydrolases family 18
Occurring in:
  1. Chitinase B
The deposited structure of PDB entry 4z2i contains 1 copy of Pfam domain PF00704 (Glycosyl hydrolases family 18) in Chitinase B. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR029070
Domain description: Chitinase insertion domain superfamily
Occurring in:
  1. Chitinase B
IPR001223
Domain description: Glycoside hydrolase family 18, catalytic domain
Occurring in:
  1. Chitinase B
IPR003610
Domain description: Carbohydrate binding module family 5/12
Occurring in:
  1. Chitinase B
IPR036573
Domain description: Carbohydrate-binding module superfamily 5/12
Occurring in:
  1. Chitinase B
IPR001579
Domain description: Glycosyl hydrolase family 18, active site
Occurring in:
  1. Chitinase B
IPR011583
Domain description: Chitinase II
Occurring in:
  1. Chitinase B
IPR017853
Domain description: Glycoside hydrolase superfamily
Occurring in:
  1. Chitinase B

Structure domains

CATH CATH domains
3.20.20.80
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Glycosidases
Occurring in:
  1. Chitinase B
The deposited structure of PDB entry 4z2i contains 1 copy of CATH domain 3.20.20.80 (TIM Barrel) in Chitinase B. Showing 1 copy in chain A.
2.10.10.20
Class: Mainly Beta
Architecture: Ribbon
Topology: Seminal Fluid Protein PDC-109 (Domain B)
Homology: Carbohydrate-binding module superfamily 5/12
Occurring in:
  1. Chitinase B
The deposited structure of PDB entry 4z2i contains 1 copy of CATH domain 2.10.10.20 (Seminal Fluid Protein PDC-109 (Domain B)) in Chitinase B. Showing 1 copy in chain A.
3.10.50.10
Class: Alpha Beta
Architecture: Roll
Topology: Chitinase A; domain 3
Homology: Chitinase A; domain 3
Occurring in:
  1. Chitinase B
The deposited structure of PDB entry 4z2i contains 1 copy of CATH domain 3.10.50.10 (Chitinase A; domain 3) in Chitinase B. Showing 1 copy in chain A.

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