Function and Biology

the plant peptide hormone receptor complex in arabidopsis

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 2.7.11.1: Non-specific serine/threonine protein kinase

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Systematic name:
ATP:protein phosphotransferase (non-specific)
Alternative Name(s):
  • A-kinase
  • AP50 kinase
  • ATP-protein transphosphorylase
  • Beta-IIPKC
  • Beta-adrenergic receptor kinase
  • CK-2
  • CKI
  • CKII
  • Calcium-dependent protein kinase C
  • Calcium/phospholipid-dependent protein kinase
  • Casein kinase
  • Casein kinase (phosphorylating)
  • Casein kinase 2
  • Casein kinase I
  • Casein kinase II
  • Cyclic AMP-dependent protein kinase
  • Cyclic AMP-dependent protein kinase A
  • Cyclic monophosphate-dependent protein kinase
  • Cyclic nucleotide-dependent protein kinase
  • Cyclin-dependent kinase
  • Cytidine 3',5'-cyclic monophosphate-responsive protein kinase
  • Dsk1
  • Epsilon PKC
  • Glycogen synthase A kinase
  • Glycogen synthase a kinase
  • Glycogen synthase kinase
  • HIPK2
  • Hpr kinase
  • Hydroxyalkyl-protein kinase
  • M phase-specific cdc2 kinase
  • MAPK
  • Mitogen-activated S6 kinase
  • Mitogen-activated protein kinase
  • P82 kinase
  • PKA
  • PKC
  • Phosphorylase B kinase kinase
  • Phosphorylase b kinase kinase
  • Phosphorylase b kinase kinase
  • Protein glutamyl kinase
  • Protein kinase (phosphorylating)
  • Protein kinase A
  • Protein kinase CK2
  • Protein kinase p58
  • Protein phosphokinase
  • Protein serine kinase
  • Protein serine-threonine kinase
  • Protein-aspartyl kinase
  • Protein-cysteine kinase
  • Protein-serine kinase
  • Prp4 protein kinase
  • Raf kinase
  • Raf-1
  • Ribosomal S6 protein kinase
  • Ribosomal protein S6 kinase II
  • STK32
  • Serine kinase
  • Serine protein kinase
  • Serine(threonine) protein kinase
  • Serine-specific protein kinase
  • Serine/threonine protein kinase
  • T-antigen kinase
  • Threonine-specific protein kinase
  • Twitchin kinase
  • Type-2 casein kinase
  • WEE1Hu
  • Wee 1-like kinase
  • Wee-kinase
  • cAMP-dependent protein kinase
  • cAMP-dependent protein kinase A
  • cGMP-dependent protein kinase

EC 2.7.10.1: Receptor protein-tyrosine kinase

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Systematic name:
ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)
Alternative Name(s):
  • AATK
  • AATYK
  • AATYK2
  • AATYK3
  • ACH
  • ALK
  • ARK
  • ATP:protein-tyrosine O-phosphotransferase
  • AXL
  • Anaplastic lymphoma kinase
  • BRT
  • Bek
  • Bfgfr
  • Bsk
  • C-FMS
  • CAK
  • CCK4
  • CD115
  • CD135
  • CDw135
  • CFD1
  • CKIT
  • CSF1R
  • Cek1
  • Cek10
  • Cek11
  • Cek2
  • Cek3
  • Cek5
  • Cek6
  • Cek7
  • DAlk
  • DDR1
  • DDR2
  • DKFZp434C1418
  • DRT
  • DTK
  • Dek
  • Drosophila Eph kinase
  • ECK
  • EDDR1
  • EGFR
  • EPH
  • EPHA1
  • EPHA2
  • EPHA6
  • EPHA7
  • EPHA8
  • EPHB1
  • EPHB2
  • EPHB3
  • EPHB4
  • EPHT
  • EPHT2
  • EPHT3
  • EPHX
  • ERBB
  • ERBB1
  • ERBB2
  • ERBB3
  • ERBB4
  • ERK
  • Ebk
  • Eek
  • Ehk2
  • Ehk3
  • Elk
  • EphB5
  • Ephrin-B3 receptor tyrosine kinase
  • Eyk
  • FGFR1
  • FGFR2
  • FGFR3
  • FGFR4
  • FLG
  • FLK1
  • FLK2
  • FLT1
  • FLT2
  • FLT3
  • FLT4
  • FMS
  • Fv2
  • HBGFR
  • HEK11
  • HEK2
  • HEK3
  • HEK5
  • HEK6
  • HEP
  • HER2
  • HER3
  • HER4
  • HGFR
  • HSCR1
  • HTK
  • IGF1R
  • INSR
  • INSRR
  • IR
  • IRR
  • Insulin receptor protein-tyrosine kinase
  • JTK12
  • JTK13
  • JTK14
  • JWS
  • K-SAM
  • KDR
  • KGFR
  • KIA0641
  • KIAA1079
  • KIAA1459
  • KIT
  • KLG
  • Kil
  • Kin15
  • Kin16
  • LTK
  • MCF3
  • MEN2A/B
  • MER
  • MERTK
  • MET
  • MEhk1
  • MST1R
  • MTC1
  • MUSK
  • Mdk1
  • Mdk2
  • Mdk5
  • Mep
  • Mlk1
  • Mlk2
  • Mrk
  • Myk1
  • N-SAM
  • NEP
  • NET
  • NGL
  • NOK
  • NTRK1
  • NTRK2
  • NTRK3
  • NTRK4
  • NTRKR1
  • NTRKR2
  • NTRKR3
  • NYK
  • Neu
  • Neurite outgrowth regulating kinase
  • Nork
  • Novel oncogene with kinase-domain
  • Nsk2
  • Nuk
  • PCL
  • PDGFR
  • PDGFRA
  • PDGFRB
  • PHB6
  • PTK
  • PTK3
  • PTK7
  • Protein tyrosine kinase
  • Protein-tyrosine kinase
  • RET
  • RON
  • ROR1
  • ROR2
  • ROS1
  • RSE
  • RTK
  • RYK
  • Receptor protein tyrosine kinase
  • SEA
  • SKY
  • STK
  • STK1
  • Sek2
  • Sek3
  • Sek4
  • Sfr
  • TEK
  • TIE
  • TIE1
  • TIE2
  • TIF
  • TKT
  • TRK
  • TRKA
  • TRKB
  • TRKC
  • TRKE
  • TYK1
  • TYRO10
  • TYRO3
  • TYRO7
  • Tyro11
  • Tyro5
  • Tyro6
  • UFO
  • VEGFR1
  • VEGFR2
  • VEGFR3
  • Vik
  • YK1
  • Yrk

EC 4.6.1.2: Guanylate cyclase

Reaction catalysed:
GTP = 3',5'-cyclic GMP + diphosphate
Systematic name:
GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming)
Alternative Name(s):
  • GTP diphosphate-lyase (cyclizing)
  • Guanyl cyclase
  • Guanylyl cyclase

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00560
Domain description: Leucine Rich Repeat
Occurring in:
  1. Phytosulfokine receptor 1
  2. Somatic embryogenesis receptor kinase 1
The deposited structure of PDB entry 4z64 contains 3 copies of Pfam domain PF00560 (Leucine Rich Repeat) in Phytosulfokine receptor 1. Showing 3 copies in chain A.
The deposited structure of PDB entry 4z64 contains 4 copies of Pfam domain PF00560 (Leucine Rich Repeat) in Somatic embryogenesis receptor kinase 1. Showing 4 copies in chain B [auth C].

PF13855
Domain description: Leucine rich repeat
Occurring in:
  1. Phytosulfokine receptor 1
The deposited structure of PDB entry 4z64 contains 2 copies of Pfam domain PF13855 (Leucine rich repeat) in Phytosulfokine receptor 1. Showing 2 copies in chain A.

PF08263
Domain description: Leucine rich repeat N-terminal domain
Occurring in:
  1. Phytosulfokine receptor 1
  2. Somatic embryogenesis receptor kinase 1
The deposited structure of PDB entry 4z64 contains 1 copy of Pfam domain PF08263 (Leucine rich repeat N-terminal domain) in Phytosulfokine receptor 1. Showing 1 copy in chain A.
The deposited structure of PDB entry 4z64 contains 1 copy of Pfam domain PF08263 (Leucine rich repeat N-terminal domain) in Somatic embryogenesis receptor kinase 1. Showing 1 copy in chain B [auth C].

InterPro InterPro annotations
IPR001611
Domain description: Leucine-rich repeat
Occurring in:
  1. Phytosulfokine receptor 1
  2. Somatic embryogenesis receptor kinase 1
IPR003591
Domain description: Leucine-rich repeat, typical subtype
Occurring in:
  1. Phytosulfokine receptor 1
IPR032675
Domain description: Leucine-rich repeat domain superfamily
Occurring in:
  1. Phytosulfokine receptor 1
  2. Somatic embryogenesis receptor kinase 1
IPR013210
Domain description: Leucine-rich repeat-containing N-terminal, plant-type
Occurring in:
  1. Phytosulfokine receptor 1
  2. Somatic embryogenesis receptor kinase 1

Structure domain

CATH CATH domain
3.80.10.10
Class: Alpha Beta
Architecture: Alpha-Beta Horseshoe
Topology: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)
Homology: Ribonuclease Inhibitor
Occurring in:
  1. Somatic embryogenesis receptor kinase 1
The deposited structure of PDB entry 4z64 contains 1 copy of CATH domain 3.80.10.10 (Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)) in Somatic embryogenesis receptor kinase 1. Showing 1 copy in chain B [auth C].