› 4zas

X-ray diffraction
2.47Å resolution

Crystal structure of sugar aminotransferase CalS13 from Micromonospora echinospora

Released:
DOI: 10.2210/pdb4zas/pdb
PDB entry 4zas coloured by chain, front view.
PDB entry 4zas coloured by chain, side view.
PDB entry 4zas coloured by chain, top view.
Source organism: Micromonospora echinospora
Entry authors: Wang F, Singh S, Miller MD, Thorson JS, Phillips Jr GN, Enzyme Discovery for Natural Product Biosynthesis (NatPro)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185172 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
dTDP-4-amino-4,6-dideoxygalactose transaminase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 404 amino acids
Theoretical weight: 44.46 KDa
Source organism: Micromonospora echinospora
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8KND8 (Residues: 1-376; Coverage: 100%)
Gene name: calS13
Sequence domains: DegT/DnrJ/EryC1/StrS aminotransferase family
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand SO4 2 x SO4
Ligand T46 1 x T46
Ligand TYD 3 x TYD
1 modified residue:
Ligand LLP 6 x LLP

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P21
Unit cell:
a: 71.57Å b: 88.74Å c: 189.81Å
α: 90° β: 96.22° γ: 90°
R-values:
R R work R free
0.174 0.173 0.229
Expression system: Escherichia coli BL21(DE3)

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