4zlt

X-ray diffraction
3Å resolution

Crystal structure of viral chemokine binding protein R17 in complex with CCL3

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-514125 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Putative uncharacterized protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 420 amino acids
Theoretical weight: 47.39 KDa
Source organism: Cricetid gammaherpesvirus 2
Expression system: Mammalian expression vector pBGSA
UniProt:
  • Canonical: E9M5R0 (Residues: 28-439; Coverage: 94%)
Gene names: RHVP-L.R17, RHVP.R17
C-C motif chemokine 3 Chains: F, L
Molecule details ›
Chains: F, L
Length: 70 amino acids
Theoretical weight: 7.98 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P10855 (Residues: 24-92; Coverage: 100%)
Gene names: Ccl3, Mip1a, Scya3
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: I222
Unit cell:
a: 98.493Å b: 109.482Å c: 210.956Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.215 0.274
Expression systems:
  • Mammalian expression vector pBGSA
  • Escherichia coli