Function and Biology Details
Reaction catalysed:
NAD(+) + H(2)O = ADP-D-ribose + nicotinamide
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Translational (tr)-type GTP-binding domain
- P-loop containing nucleoside triphosphate hydrolase
- Bacterial toxin 46
- Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
- Translation elongation factor EFTu/EF1A, C-terminal
- Translation elongation factor EFTu-like, domain 2
- Elongation factor Tu, domain 2
- Translation protein, beta-barrel domain superfamily
4 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140702 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Elongation factor Tu
Molecule details ›
Chains: A, B
Length: 405 amino acids
Theoretical weight: 44.49 KDa
Source organism: Pseudomonas aeruginosa PAO1
Expression system: Escherichia coli BL21
UniProt:
Sequence domains:
Length: 405 amino acids
Theoretical weight: 44.49 KDa
Source organism: Pseudomonas aeruginosa PAO1
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P09591 (Residues: 1-397; Coverage: 100%)
Sequence domains:
- Elongation factor Tu GTP binding domain
- Elongation factor Tu domain 2
- Elongation factor Tu C-terminal domain
NAD(P)(+) glycohydrolase toxin Tse6
Molecule details ›
Chains: C, D
Length: 180 amino acids
Theoretical weight: 20.12 KDa
Source organism: Pseudomonas aeruginosa PAO1
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Bacterial toxin 46
Length: 180 amino acids
Theoretical weight: 20.12 KDa
Source organism: Pseudomonas aeruginosa PAO1
Expression system: Escherichia coli BL21
UniProt:
- Canonical: Q9I739 (Residues: 265-430; Coverage: 39%)
Sequence domains: Bacterial toxin 46
