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Crystal structure of maltose-bound human GLUT3 in the outward-open conformation at 2.6 angstrom

Source organism: Homo sapiens
Biochemical function: D-glucose transmembrane transporter activity
Biological process: D-glucose transmembrane transport
Cellular component: ficolin-1-rich granule membrane

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00083
Domain description: Sugar (and other) transporter
Occurring in:
  1. Solute carrier family 2, facilitated glucose transporter member 3
The deposited structure of PDB entry 4zwc contains 2 copies of Pfam domain PF00083 (Sugar (and other) transporter) in Solute carrier family 2, facilitated glucose transporter member 3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003663
Domain description: Sugar/inositol transporter
Occurring in:
  1. Solute carrier family 2, facilitated glucose transporter member 3
IPR002945
Domain description: Glucose transporter, type 3 (GLUT3)
Occurring in:
  1. Solute carrier family 2, facilitated glucose transporter member 3
IPR005829
Domain description: Sugar transporter, conserved site
Occurring in:
  1. Solute carrier family 2, facilitated glucose transporter member 3
IPR036259
Domain description: MFS transporter superfamily
Occurring in:
  1. Solute carrier family 2, facilitated glucose transporter member 3
IPR005828
Domain description: Major facilitator, sugar transporter-like
Occurring in:
  1. Solute carrier family 2, facilitated glucose transporter member 3
IPR020846
Domain description: Major facilitator superfamily domain
Occurring in:
  1. Solute carrier family 2, facilitated glucose transporter member 3
IPR045263
Domain description: Glucose transporter GLUT
Occurring in:
  1. Solute carrier family 2, facilitated glucose transporter member 3

Structure domain

CATH CATH domain
1.20.1250.20
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Growth Hormone; Chain: A;
Homology: MFS general substrate transporter like domains
Occurring in:
  1. Solute carrier family 2, facilitated glucose transporter member 3
The deposited structure of PDB entry 4zwc contains 2 copies of CATH domain 1.20.1250.20 (Growth Hormone; Chain: A;) in Solute carrier family 2, facilitated glucose transporter member 3. Showing 1 copy in chain A.

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