› 5a1m

X-ray diffraction
1.81Å resolution

Crystal structure of calcium-bound human adseverin domain A3

Released:
DOI: 10.2210/pdb5a1m/pdb
PDB entry 5a1m coloured by chain, front view.
PDB entry 5a1m coloured by chain, side view.
PDB entry 5a1m coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Calcium-controlled conformational choreography in the N-terminal half of adseverin.
Chumnarnsilpa S, Robinson RC, Grimes JM, Leyrat C
OpenAccess logo Nat Commun 6 8254 (2015)
PMID: 26365202

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-578983 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Scinderin Chain: A
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 11.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y6U3 (Residues: 247-350; Coverage: 15%)
Gene names: KIAA1905, SCIN
Sequence domains: Gelsolin repeat
Structure domains: Severin

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: I422
Unit cell:
a: 92.51Å b: 92.51Å c: 68.91Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.182 0.189
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology.
Brosey et al. (2019)
3 more

1 mention without citation

Calcium-controlled conformational choreography in the N-terminal half of adseverin.
Chumnarnsilpa et al. (2015)