5bxv

X-ray diffraction
2.1Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-549462 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Eukaryotic translation initiation factor 4E Chains: A, C
Molecule details ›
Chains: A, C
Length: 192 amino acids
Theoretical weight: 22.33 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P63073 (Residues: 27-217; Coverage: 88%)
Gene name: Eif4e
Sequence domains: Eukaryotic initiation factor 4E
Structure domains: RNA Cap, Translation Initiation Factor Eif4e
Eukaryotic translation initiation factor 4E-binding protein 1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 44 amino acids
Theoretical weight: 4.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13541 (Residues: 43-84; Coverage: 36%)
Gene name: EIF4EBP1
Sequence domains: Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 67.607Å b: 67.83Å c: 79.084Å
α: 90° β: 112.43° γ: 90°
R-values:
R R work R free
0.163 0.162 0.195
Expression system: Escherichia coli