› 5c9k

X-ray diffraction
1.92Å resolution

Crystal structure of a highly fibrillogenic Arg24Gly mutant of the Recombinant variable domain 6AJL2

Released:
DOI: 10.2210/pdb5c9k/pdb
PDB entry 5c9k coloured by chain, front view.
PDB entry 5c9k coloured by chain, side view.
PDB entry 5c9k coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Hernandez-Santoyo A, Rodriguez-Romero A, Luna-Martinez OD, Becerril-Lujan B

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-188571 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ig-like domain-containing protein Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 111 amino acids
Theoretical weight: 11.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96JD1 (Residues: 1-111; Coverage: 99%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand ACT 4 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: C2
Unit cell:
a: 104.556Å b: 95.633Å c: 102.583Å
α: 90° β: 96° γ: 90°
R-values:
R R work R free
0.172 0.17 0.219
Expression system: Escherichia coli

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