› 5dtb

X-ray diffraction
1.84Å resolution

Crystal structure of the Drosophila CG3822 KaiR1D ligand binding domain complex with glutamate

Released:
DOI: 10.2210/pdb5dtb/pdb
PDB entry 5dtb coloured by chain, front view.
PDB entry 5dtb coloured by chain, side view.
PDB entry 5dtb coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Li Y, Dharkar P, Han TH, Serpe M, Lee CH, Mayer ML
Neuron 92 1036-1048 (2016)
PMID: 27889096

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194231 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kainate-type ionotropic glutamate receptor subunit 1D Chains: A, B
Molecule details ›
Chains: A, B
Length: 267 amino acids
Theoretical weight: 29.78 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9VDH5 (Residues: 411-527, 650-794; Coverage: 32%)
Gene names: CG3822, CT12759, DKaiR1D, DKaiRID, DmelCG3822, Dmel\CG3822, Dmel_CG3822, KaiR1D, KaiRID, dKaiR1D
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

3 bound ligands:
Ligand GLU 2 x GLU
Ligand GOL 2 x GOL
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P43212
Unit cell:
a: 87.704Å b: 87.704Å c: 183.341Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.163 0.162 0.194
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.
Hansen et al. (2021)
4 more

1 mention without citation

Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Li et al. (2016)