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5fxs Overview
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5fxs</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-like growth factor 1 receptor beta chain</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>ACETATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5fxs_deposited_chain_front_image-800x800.png "PDB entry 5fxs coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5fxs</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-like growth factor 1 receptor beta chain</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>ACETATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5fxs_deposited_chain_side_image-800x800.png "PDB entry 5fxs coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5fxs</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-like growth factor 1 receptor beta chain</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>ACETATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5fxs_deposited_chain_top_image-800x800.png "PDB entry 5fxs coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5fxs</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-like growth factor 1 receptor beta chain</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>ACETATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5fxs_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 5fxs coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5fxs</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-like growth factor 1 receptor beta chain</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>ACETATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5fxs_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 5fxs coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5fxs</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-like growth factor 1 receptor beta chain</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>ACETATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5fxs_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 5fxs coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5fxs</span> contains 1 copy of <span class='highlight'>2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide</span>. Front view.</div>](https://www.ebi.ac.uk/pdbe/static/entry/5fxs_entity_3_front_image-800x800.png "2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide in PDB entry 5fxs, assembly 1, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5fxs</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-like growth factor 1 receptor beta chain</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>ACETATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5fxs_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Monomeric assembly 1 of PDB entry 5fxs coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5fxs</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-like growth factor 1 receptor beta chain</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>ACETATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5fxs_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Monomeric assembly 1 of PDB entry 5fxs coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5fxs</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Insulin-like growth factor 1 receptor beta chain</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>ACETATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5fxs_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Monomeric assembly 1 of PDB entry 5fxs coloured by chemically distinct molecules, top view.")