5gs6

X-ray diffraction
2.85Å resolution

Full-length NS1 structure of Zika virus from 2015 Brazil strain

Released:

Function and Biology Details

Reactions catalysed:
Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-102845 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NS1 of Zika virus from 2015 Brazil strain Chains: A, B
Molecule details ›
Chains: A, B
Length: 357 amino acids
Theoretical weight: 40.87 KDa
Source organism: Zika virus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A0A109PRQ3 (Residues: 796-1146; Coverage: 10%)
Sequence domains: Flavivirus non-structural Protein NS1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P4122
Unit cell:
a: 96.948Å b: 96.948Å c: 270.143Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.246 0.244 0.284
Expression system: Trichoplusia ni