› 5hmo

X-ray diffraction
3.49Å resolution

myosin X motor activity

Released:
DOI: 10.2210/pdb5hmo/pdb
PDB entry 5hmo coloured by chain, front view.
PDB entry 5hmo coloured by chain, side view.
PDB entry 5hmo coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
The myosin X motor is optimized for movement on actin bundles.
Ropars V, Yang Z, Isabet T, Blanc F, Zhou K, Lin T, Liu X, Hissier P, Samazan F, Amigues B, Yang ED, Park H, Pylypenko O, Cecchini M, Sindelar CV, Sweeney HL, Houdusse A
OpenAccess logo Nat Commun 7 12456 (2016)
PMID: 27580874

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160316 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Unconventional myosin-X Chains: A, C
Molecule details ›
Chains: A, C
Length: 134 amino acids
Theoretical weight: 16.68 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P79114 (Residues: 796-929; Coverage: 7%)
Gene name: MYO10
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P43212
Unit cell:
a: 69.81Å b: 69.81Å c: 236.69Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.394 0.391 0.437
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

8 review citations

MyTH4-FERM myosins in the assembly and maintenance of actin-based protrusions.
Weck et al. (2017)
7 more

1 mention without citation

The myosin X motor is optimized for movement on actin bundles.
Ropars et al. (2016)