› 5jcr

X-ray diffraction
1.7Å resolution

Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl alpha-D-mannopyrannoside in spacegroup P212121

Released:
DOI: 10.2210/pdb5jcr/pdb
PDB entry 5jcr coloured by chain, front view.
PDB entry 5jcr coloured by chain, side view.
PDB entry 5jcr coloured by chain, top view.
Source organism: Escherichia coli K-12
Entry authors: Jakob RP, Rabbani S, Ernst B, Maier T

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140004 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Type 1 fimbrin D-mannose specific adhesin Chains: A, B
Molecule details ›
Chains: A, B
Length: 158 amino acids
Theoretical weight: 16.92 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P08191 (Residues: 22-179; Coverage: 57%)
Gene names: JW4283, b4320, fimH
Sequence domains: FimH, mannose binding
Structure domains: Fimbrial-type adhesion domain

Ligands and Environments

1 bound ligand:
Ligand MMA 2 x MMA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 62.98Å b: 68.95Å c: 95.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.209 0.23
Expression system: Escherichia coli BL21(DE3)

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