5jq3

X-ray diffraction
2.23Å resolution

Crystal structure of Ebola glycoprotein

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170177 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
GP1 Chain: A
Molecule details ›
Chain: A
Length: 332 amino acids
Theoretical weight: 36.47 KDa
Source organism: Ebola virus - Mayinga, Zaire, 1976
Expression system: Homo sapiens
UniProt:
  • Canonical: Q05320 (Residues: 32-501; Coverage: 49%)
Gene name: GP
Sequence domains: Filovirus glycoprotein
GP2 Chain: B
Molecule details ›
Chain: B
Length: 168 amino acids
Theoretical weight: 18.99 KDa
Source organism: Ebola virus - Mayinga, Zaire, 1976
Expression system: Homo sapiens
UniProt:
  • Canonical: Q05320 (Residues: 502-632; Coverage: 20%)
Gene name: GP
Sequence domains: Envelope glycoprotein GP2-like, HR1-HR2

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: R32
Unit cell:
a: 114.258Å b: 114.258Å c: 307.377Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.223 0.222 0.246
Expression system: Homo sapiens