› 5l74

X-ray diffraction
1.36Å resolution

Plexin A2 extracellular segment domains 4-5 (PSI2-IPT2), resolution 1.36 Angstrom

Released:
DOI: 10.2210/pdb5l74/pdb
PDB entry 5l74 coloured by chain, front view.
PDB entry 5l74 coloured by chain, side view.
PDB entry 5l74 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural Basis for Plexin Activation and Regulation.
Kong Y, Janssen BJ, Malinauskas T, Vangoor VR, Coles CH, Kaufmann R, Ni T, Gilbert RJ, Padilla-Parra S, Pasterkamp RJ, Jones EY
OpenAccess logo Neuron 91 548-60 (2016)
PMID: 27397516

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159714 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plexin-A2 Chain: A
Molecule details ›
Chain: A
Length: 151 amino acids
Theoretical weight: 16.91 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P70207 (Residues: 655-803; Coverage: 8%)
Gene names: Kiaa0463, Plxna2
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand NAG 3 x NAG
Ligand NA 2 x NA
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: C2
Unit cell:
a: 107.71Å b: 44.56Å c: 33.01Å
α: 90° β: 104.7° γ: 90°
R-values:
R R work R free
0.176 0.174 0.202
Expression system: Homo sapiens

Quick links

Citations

14 review citations

TREM2-Ligand Interactions in Health and Disease.
Kober et al. (2017)
13 more